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Boutique Key West Hotel Accommodations

Enjoy Oceanfront Views and Modern Amenities by our Historic Bed and Breakfast

Welcome to the famous The Southernmost House in Key West, Florida. Inside our historic bed and breakfast in the Florida Keys, you'll find beautifully restored Key West hotel accommodations that radiate the magnificent ambiance of our tropical paradise.  

Located on the calmer end of Duval Street in historic Old Town Key West and directly on the Atlantic Ocean, The Southernmost House is a premier boutique hotel nestled along the water, with all the amenities of a Key West bed and breakfast. Each one of our 18 hotel rooms is unique and offers a special design and personality to enhance your stay in Key West. Read below and find the perfect accommodation to complement your vacation in the Florida Keys. Book online for the best rate available.

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Ocean View Suites

The Southernmost House offers Key West’s most desired suites. With spectacular ocean views, each suite offers the best in luxurious amenities in a truly stunning setting. Each Suite provides stately hotel amenities, including plush King beds, a generous private bathroom, air conditioning, and panoramic views of the Caribbean.

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Ocean View Rooms with Balcony

Opt for extra space when you reserve one of Key West’s most desired ocean view rooms at The Southernmost House. Each room offers stately hotel amenities, including plush King beds, a generous private bathroom, and air conditioning. Enjoy panoramic views of the Caribbean from your balcony. This is an ideal setting for socializing or enjoying a beverage while taking in the gorgeous ocean views.

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Ocean View Rooms

Immerse yourself in comfortable Key West lodging with magnificent ocean views. Individually styled, every Ocean View Hotel Room provides stately amenities, including a plush King or Queen-Size bed, a spacious private bathroom, air conditioning, and panoramic views of the Caribbean.

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Courtyard View Rooms

Relax and enjoy island life in one of our Courtyard View Hotel Rooms. These elegant Key West accommodations, feature stately hotel amenities, spacious private bathrooms, air conditioning, and panoramic views of our courtyard.

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The Lopez House

The Lopez House is our detached guesthouse in Key West, Florida. It’s the only 5-bedroom, 5-bath oceanfront house in Key West and can be rented as a single vacation rental. The beautiful rooms and wrap around balconies on both the first and second floors are perfect for large families or friends looking for spacious Key West lodging. The Lopez House includes the Lopez Suite which offers a kitchen with full size appliances and a dining room. Enjoy home cooked meals while you look out over vast ocean views. The Lopez House also includes a handicap accessible room with direct access to the wrap around porch.

1400 Duval St, Key West,
FL 33040 (305) 296-3141